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Title: A Closer Look at Kinase Inhibition
Edited by: Alex Tompson
ISBN10-13: 1536169730 : 9781536169737
Format: Hardback
Size: 1x1mm
Pages: 212
Weight: .418 Kg.
Published: Nova Science Publishers, Inc - February   2020
List Price: 141.99 Pounds Sterling
Availability: In Stock   Qty Available: 2
Subjects: Chemistry
A Closer Look at Kinase Inhibition opens with a discussion on the roles of various tyrosine kinases inhibitors and molecular mechanisms of acquired resistance to tyrosine kinase inhibitor drugs therapy in colon-rectal cancer. The authors summarize host cell and viral protein kinases, the progress in their use, and the repurposing of approved kinase inhibitors as broad-spectrum antivirals. The key kinases, namely CLK1, DYRK1A, CDK5, GSK3 and CK1, are analyzed as data indicate that targeting these proteins may have therapeutic promise against Alzheimer's disease.
Table of Contents:
  • Preface
  • Targeted Therapy of Tyrosine Kinase Inhibitor Drugs for Two Different Cancers (Colon-Rectal Cancer and Chronic Myelogenous Leukemia) and Their Resistance Mechanisms
  • Role of Kinases in Antiviral Therapeutics
  • In Search of Novel Tau Kinase Inhibitors and Their Role in Alzheimer’s Therapy
  • Index.
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