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Title: Trends in Cellular Signaling
By (author): Dave E Caplin
ISBN10-13: 1594546339 : 9781594546334
Illustrations: tables & charts
Format: Hardback
Size: 180x260mm
Pages: 238
Weight: .752 Kg.
Published: Nova Science Publishers, Inc (US) - May   2006
List Price: 230.99 Pounds Sterling
Availability: Temporarily Out of Stock, more expected soon 
Subjects: Medical genetics
Cell signalling is the communication inside a cell or with its environment. It plays an important role in cellular growth, survival and apoptosis. For instance, the growth of a cell requires production of certain proteins. The genes that encode these proteins are located in DNA inside the nucleus while the initial signal for cellular growth may come from outside the cell. To induce the expression of these genes, the external signal must pass through specific pathways to reach these genes in DNA. The signalling pathway involves several proteins. If any one of them becomes abnormal or non-functional, the cellular process would be altered, which may cause disease. Therefore, knowing the detailed pathway is very important in understanding the pathogenesis of diseases.
Table of Contents:
Preface; FMLP-OMe Analogues Trigger Specific Signalling Pathways in the Physiological Functions of Human Neutrophils; Transcription of Genes in Response to Activated cAMP/PROTEIN Kinase a Signalling Pathway: There is More to it Than Creb; MEN2A and MEN2B Syndromes: A Unique Gene for Two Diseases; Signalling to Hypoxia-Inducible Factor-1 Activation and its Role in the Pathogensis of Diseases; Wnt Signalling in Normal Development and Cancer Progression; Index.
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