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Title: Trends in Cox-2 Inhibitor Research
Edited by: Maynard J Howardell
ISBN10-13: 1600212220 : 9781600212222
Illustrations: tables & charts
Format: Hardback
Size: 180x260mm
Pages: 169
Weight: .602 Kg.
Published: Nova Science Publishers, Inc (US) - May   2006
List Price: 154.99 Pounds Sterling
Availability: In Stock   Qty Available: 1
Subjects: Medical research : Pharmacology
Cox-2 Inhibitors are newly developed drugs for inflammation that selectively block the Cox-2 enzyme. Blocking this enzyme impedes the production of the chemical messengers (prostaglandins) that cause the pain and swelling of arthritis inflammation. Cox-2 inhibitors are a new class of non-steroidal anti-inflammatory drugs (NSAIDS). Because they selectively block the Cox-2 enzyme and not the Cox-1 enzyme, these drugs are uniquely different from traditional NSAIDS. This book explores new research in the field.
Table of Contents:
Preface; NSAIDs in Animal Models of Alzheimer’s Disease; Relevance of COX-2 Inhibitors in Alzheimer’s Disease; COX.1-COX.2 Simultaneous Inhibitory Mechanism in Gastric Injury and COX.2-COX.3 in Small Intestine Injury; Effects of Cox-2 Inhibitors on Brain Diseases; Cyclooxygenase-2 Overexpression and the Chemopreventive and Therapeutic Uses of Cyclooxygenase Inhibitors in Lung Cancer; Safety Monitoring of Celecoxib and Rofecoxib in the New Zealand Intensive Medicines Monitoring Programme; The Effect of COX-2 Inhibitor in Osteoarthritic Chondrocytes; Index.
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