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Title: Tubulin
Sub-title: Structure, Functions & Roles in Disease
Edited by: Wei Yamauchi, Antonio Sokić
ISBN10-13: 1621001415 : 9781621001416
Format: Hardback
Size: 260x180mm
Pages: 0
Weight: .554 Kg.
Published: Nova Science Publishers, Inc (US) - August   2012
List Price: 194.99 Pounds Sterling
Availability: Temporarily Out of Stock, more expected soon 
Subjects: Biochemistry
Tubulin is one of several members of a small family of globular proteins. The most common members of the tubulin family are α-tubulin and β-tubulin, the proteins that make up microtubules. In this book the authors present topical research in the study of the structure, functions and roles in disease of tubulin. Topics discussed in this compilation include microtubule plus-end tracking proteins in neuronal development and nervous system disorders; trypanosome tubulin molecules as targets for drug and vaccine development for protozoan infections; tubulin inhibitors as vascular disrupting agents and evolution and co-evolution of tubulin's carboxy-terminal tails and mitochondria.
Table of Contents:
Preface; Microtubule Plus-End Tracking Proteins in Neuronal Development & Nervous System Disorders; Microtubule Organization: The Housekeeping Role of Heat-Shock Proteins & Immunophilins; Trypanosome Tubulin Molecules as Targets for Drug & Vaccine Development for Protozoan Infections; Tubulin: Structure, Function, & Role in Disease; Targeted Disruption of the Tubulin Cytoskeletal Network Activates Expression of the Profibrotic Genes PAI-1 & CTGF: Implications for Vascular Disease; Tubulin Inhibitors as Vascular Disrupting Agents (VDAS); Evolution & Coevolution of Tubulin’s Carboxy-Terminal Tails & Mitochondria; Myelin Basic Protein Interactions with Actin & Tubulin in vitro – Binding, Assembly, & Regulation; Index.
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